Emperor Valens orders the governor of Asia Minor to exterminate the Hellenes and destroy all writings of their wisdom.
The majority of the Gentiles of Asia Minor are exterminated, after a desperate revolt against the Emperor and the Church.
* This needs to be substantiated, as the claim seems excessive.
The inquisitor Ioannis Asiacus, a fanatical monk, leads a crusade against the Gentiles of Asia Minor.
Constantine sacks many Pagan Temples of Asia Minor and Palestine and orders the execution by crucifixion of “all magicians and soothsayers". Martyrdom of the neoplatonist philosopher Sopatros.
"Emperor Constantine, following the instructions of his mother Helen, destroys the Temple of the God Asclepius in Aigeai of Cilicia and many Temples of the Goddess Aphrodite in Jerusalem, Aphaca, Mambre, Phoenice, Baalbek, etc."